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Injecting tiny beads into the arteries
that feed painful fibroids in the uterus can be better than
surgery for most women, even if the long-term risk of
complications is higher, researchers reported on Wednesday.
About 30 percent of all women over the age of 30 develop
the benign tumors, which are responsible for about 13,000
hysterectomies in Britain alone each year. Fibroids can cause
pain, heavy menstrual bleeding, pressure on the bladder, or
bowel obstruction.
Hysterectomy once was the only treatment, but now other
options are available, including the bead treatment, known as
uterine-artery embolization. Once injected, the beads cut off
the supply of blood to the fibroids, shrinking or killing them.
The new study, conducted at 27 British hospitals and led by
Jonathan Moss of Gartnavel General Hospital in Glasgow, found
that the 106 women who received the treatment fared just as
well as the 51 who had the conventional surgery -- either a
hysterectomy to remove the uterus or a myomectomy to remove the
fibroids.
The patients getting the beads typically spent one day in
the hospital, compared to five days for the women receiving the
surgery; they also returned to work sooner.
But one year after the operation, the women who received
the surgery were a little less likely to still have
fibroid-related problems, the researchers reported in
Thursday's New England Journal of Medicine.
Ten of the 106 women in the embolization group needed some
type of additional treatment for their symptoms during the
first year. "After the first year of follow-up, 11 additional
women were admitted for the same indication," the Moss team
wrote.
For women whose fibroids are causing problems, "the faster
recovery after embolization must be weighed against the need
for further treatment in a minority of patients," they said.
Embolization, introduced in 1995, involves cutting into a
leg artery and snaking a hollow tube into the blood vessels
that feed the fibroids. Doctors then release the beads into the
arteries. As the artery narrows, the beads begin to clog it,
starving the fibroid of oxygen and nutrients.
One year after treatment, 93 percent of the women who had
surgery said they would recommend that option to a friend,
while 88 percent who received embolization said they would
recommend the technique.
Previous research has shown that after six years, the
fibroids return in up to 27 percent of women treated with
embolization.
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